Annual report pursuant to Section 13 and 15(d)

Stock-Based Compensation (Details Textual)

v2.4.0.8
Stock-Based Compensation (Details Textual) (USD $)
0 Months Ended 1 Months Ended 6 Months Ended 12 Months Ended 24 Months Ended 101 Months Ended 1 Months Ended 12 Months Ended 0 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended 12 Months Ended 12 Months Ended 0 Months Ended 1 Months Ended 12 Months Ended 0 Months Ended 1 Months Ended 0 Months Ended 1 Months Ended 3 Months Ended 12 Months Ended 0 Months Ended 12 Months Ended 0 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended 6 Months Ended 0 Months Ended 1 Months Ended 6 Months Ended 12 Months Ended 0 Months Ended 3 Months Ended 12 Months Ended 0 Months Ended 12 Months Ended 24 Months Ended 12 Months Ended
Oct. 15, 2009
Jan. 31, 2009
Jan. 31, 2008
Jun. 30, 2007
Feb. 05, 2007
Feb. 28, 2013
Aug. 31, 2011
May 31, 2011
Jun. 30, 2011
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2008
Jun. 30, 2008
Dec. 31, 2013
Jan. 28, 2014
Subsequent Event [Member]
Dec. 31, 2013
Subsequent Event [Member]
Dec. 31, 2013
New Transactions [Member]
Dec. 31, 2012
New Transactions [Member]
Dec. 31, 2012
Transactions Requiring-Re Evaluation In Prior Periods [Member]
Sep. 30, 2012
Transactions Requiring-Re Evaluation In Prior Periods [Member]
Jun. 30, 2006
Dr Mullinix [Member]
Dec. 31, 2013
Dr Mullinix [Member]
Dec. 31, 2012
Dr Mullinix [Member]
Dec. 31, 2013
Dr. Von Hoff [Member]
Dec. 31, 2013
Dr. Von Hoff [Member]
Subsequent Event [Member]
Aug. 31, 2008
Madajewicz [Member]
Dec. 31, 2013
Dr. Royds [Member]
Dec. 31, 2012
Dr. Royds [Member]
Dec. 31, 2012
Maximum [Member]
New Transactions [Member]
Dec. 31, 2012
Maximum [Member]
Transactions Requiring-Re Evaluation In Prior Periods [Member]
Dec. 31, 2012
Minimum [Member]
New Transactions [Member]
Dec. 31, 2012
Minimum [Member]
Transactions Requiring-Re Evaluation In Prior Periods [Member]
Sep. 11, 2012
Chem Master Agreement [Member]
Feb. 04, 2012
Chem Master Agreement [Member]
Feb. 28, 2011
Chem Master Agreement [Member]
Jan. 31, 2008
Chem Master Agreement [Member]
Feb. 28, 2007
Chem Master Agreement [Member]
Aug. 31, 2009
Chem Master Agreement [Member]
Feb. 28, 2009
Chem Master Agreement [Member]
Dec. 31, 2012
Chem Master Agreement [Member]
Jan. 28, 2008
Chem Master Agreement [Member]
Sep. 30, 2012
Consulting Agreement [Member]
Sep. 11, 2012
Consulting Agreement [Member]
Sep. 30, 2007
Consulting Agreement [Member]
Sep. 30, 2011
Consulting Agreement [Member]
Oct. 15, 2009
Consulting Agreement [Member]
Sep. 30, 2008
Consulting Agreement [Member]
Sep. 30, 2007
Consulting Agreement [Member]
Dec. 31, 2012
Consulting Agreement [Member]
Dec. 31, 2009
Consulting Agreement [Member]
Sep. 30, 2007
Consulting Agreement [Member]
Sep. 12, 2007
Consulting Agreement [Member]
Sep. 19, 2008
Consulting Agreement With Francis Johnson [Member]
Sep. 30, 2007
Consulting Agreement With Francis Johnson [Member]
Sep. 12, 2007
Consulting Agreement With Francis Johnson [Member]
Dec. 31, 2007
Mirador Agreement [Member]
Jun. 30, 2011
Outside Director Stock Award Plan [Member]
Jun. 30, 2006
Outside Director Stock Award Plan [Member]
Jun. 30, 2011
Outside Director Stock Award Plan [Member]
Jun. 30, 2006
Outside Director Stock Award Plan [Member]
Dec. 31, 2013
Outside Director Stock Award Plan [Member]
Dec. 31, 2012
Outside Director Stock Award Plan [Member]
Feb. 28, 2013
Outside Director Stock Award Plan [Member]
Jun. 30, 2006
Outside Director Additional Stock Award Plan [Member]
Dec. 31, 2006
Outside Director Additional Stock Award Plan [Member]
Jun. 30, 2006
Scientific Advisory Committee Members [Member]
Jul. 31, 2011
Scientific Advisory Committee Members [Member]
Jun. 30, 2011
Scientific Advisory Committee Members [Member]
Jun. 30, 2006
Scientific Advisory Committee Members [Member]
Dec. 31, 2013
Scientific Advisory Committee Members [Member]
Dec. 31, 2012
Scientific Advisory Committee Members [Member]
Oct. 05, 2011
Director Stock Award Plan [Member]
Sep. 30, 2009
Director Stock Award Plan [Member]
Sep. 30, 2007
Director Stock Award Plan [Member]
Apr. 19, 2011
Director Stock Award Plan [Member]
Sep. 12, 2008
Director Stock Award Plan [Member]
Sep. 12, 2009
Director Stock Award Plan [Member]
Oct. 31, 2008
Board Of Director Stock Award Plan [Member]
Dec. 31, 2008
Board Of Director Stock Award Plan [Member]
Oct. 07, 2010
Board Of Director Stock Award Plan [Member]
Dec. 31, 2011
Board and Medical Director Of Theradex Systems, Inc [Member]
May 01, 2011
Board and Medical Director Of Theradex Systems, Inc [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                                                                                                                                    
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Grants In Period, Net Of Forfeitures (in shares)               200,000 200,000 100,000 1,200,000                               8,548 97,770               200,000 100,000   100,000 500,000     500,000     1,000,000         1,000,000     300,000       200,000 200,000         190,000   100,000     50,000     500,000   200,000         200,000      
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term                   2 years 6 months 7 days             5 years 5 years     5 years                 4 years   3 years 6 months         5 years   5 years                     4 years 4 years               5 years 5 years       5 years   5 years           5 years   5 years                
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price (in dollars per share)                 $ 0.98 $ 0.843 $ 0.876     $ 0.843     $ 0.13 $ 0.65   $ 0.25     $ 0.65 $ 0.13         $ 1.00 $ 1.00 $ 0.65 $ 0.98 $ 0.65   $ 0.48   $ 0.333   $ 0.333   $ 1.65   $ 1.00             $ 1.00         $ 0.333     $ 0.333   $ 0.333     $ 0.98   $ 0.333 $ 0.333     $ 0.333     $ 1.00       $ 0.333           $ 0.98
Share Based Compensation Arrangement By Share Based Payment Award Options Vested (in shares)   25,000           25,000                                   50,000                 100,000     100,000           500,000     500,000     500,000     100,000         66,666 25,000         58,900                       100,000     25,000      
Share Based Compensation Arrangement By Share Based Payment Award Options Fair Value                 $ 49,000                           $ 118,000 $ 12,960                 $ 293,450       $ 31,000       $ 96,000   $ 286,100           $ 325,000 $ 750,000   $ 945,000     $ 300,000     $ 62,000   $ 62,000     $ 196,000                           $ 204,000   $ 0.50      
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value (in dollars per share)                             $ 0.15 $ 0.02             $ 0.59                   $ 0.59       $ 0.31           $ 0.57         $ 0.945 $ 0.65 $ 0.75       $ 1.00           $ 0.31       $ 0.31                 $ 1.02             $ 0.50 $ 0.98  
Share Based Compensation Arrangement By Share Based Payment Award Options Fair Value Charged To Operations 375,000   75,000                   41,334     134,420           58,690 31,790 125                                       465,000         210,410                     20,666 48,530 98,134               3,357 (650)                 100,000    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period (in shares)           100,000 100,000                                                     100,000                                             100,000                     15,015             200,000              
Stock Issued Shares Cash Less Exercise (in shares)                                                                                                                 66,020                                                  
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Expirations In Period (in shares)                   700,000 600,000                                                             500,000     500,000                       290,000                     34,985                            
Share Based Compensation Arrangement By Share Based Payment Award Options Vested Ratably (in shares)                       50,000                                                                                                             6,250                              
Proceeds from exercise of stock options         33,333         0 33,333     38,333                                                                                                           5,000                            
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate                               262.00% 262.00% 148.40% 128.40%                                                                                                                              
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate                               0.00% 0.00% 0.00% 0.00%                                                                                                                              
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate                               1.51% 1.51% 0.78% 0.24%                                                                                                                              
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures (in shares)                                                                       100,000                                       250,000                                                    
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures                                                                                                               250                                                    
Maximum Shares For Granting Of Awards (in shares)       2,500,000                                                                                                                                                            
Consulting Fees                                                                                                               5,000                                           40,000        
Stock Issued During Period Per Share Restricted Stock (in dollars per share)                                                                                                               $ 0.001                                                    
Fair Value Of Restricted Common Stock                                                                                                               262,250                                                    
Fair Value Of Restricted Common Stock Per Share (in dollars per share)                                                                                                               $ 1.049                                                    
Purchase Price Per Share Of Restricted Common Stock (in dollars per share)                                                                                                               $ 0.001                                                    
Stock Price Per Share Of Restricted Common Stock (in dollars per share)                                                                                                               $ 1.05                                                    
Deferred Compensation Share-based Arrangements, Liability, Classified, Noncurrent                   $ 40,000       $ 40,000                                                                                                                                        
Stock Options and Warrants Exercisable Fair Market Value (in dollars per share)                   $ 0.13 $ 0.25                                                                                                                                              
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross                                             200,000 100,000                                                                                                                    
Stock Options Vested                   150,000                         25,000   25,000                                                                                                                  
Stock Option Vested Year One                                                 25,000                                                                                                                  
Stock Option Vested Year Two                                                 25,000                                                                                                                  
Stock Option Vested Year Three                                                 25,000