June 18, 2025 - CALCULATION OF FILING FEE TABLE - S-1: General form for registration of securities under the Securities Act of 1933 | LIXTE Biotechnology Holdings, Inc. (LIXT)

Exhibit 107

Calculation of Filing Fee Table

FORM S-1

REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

(Form Type)

Lixte Biotechnology Holdings, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered Securities

Fees Previously Paid

	Security Type	Security Class Title	Fee Calculation Rule		Amount Registered		Proposed Maximum Offering Price Per Share			Maximum Aggregate Offering Price (1)		Fee Rate			Amount of Registration Fee

Newly Registered Securities

Fees to Be Paid	Equity	Common stock, par value $0.00001 per share (2)		457(o)					$	6,000,000		0.00015310		$	918.60

	Equity	Pre-Funded Warrants to purchase shares of common stock (3)		457(g)		-		-			-	-			0(4	)

	Equity	Common Stock underlying the Pre-Funded Warrants (2) (3)		457(o)		-		-			-		-			0(3	)

Fees Previously Paid	-	-		-		-		-			-		-			-

Total Offering Amounts										$	6,000,000				$	918.60
Total Fees Previously Paid										$	-				$	-
Total Fee Offsets										$	-				$	-
Net Fees Due										$	-				$	918.60

(1)	Estimated solely for the purpose of calculating the amount of the registration fee in accordance with Rule 457(o) under the Securities Act of 1933 (the “Securities Act”).
(2)	Pursuant to Rule 416 under the Securities Act, the securities registered hereby also include an indeterminate number of additional securities as may from time to time become issuable by reason of stock splits, stock dividends, recapitalizations, or other similar transactions.
(3)	The proposed maximum aggregate offering price of the common stock will be reduced on a dollar-for-dollar basis based on the offering price of any pre-funded warrants issued in the offering, and the proposed maximum aggregate offering price of the pre-funded warrants to be issued in the offering will be reduced on a dollar-for-dollar basis based on the offering price of any common stock issued in the offering. Accordingly, the proposed maximum aggregate offering price of the common stock and pre-funded warrants (including the common stock issuable upon exercise of the pre-funded warrants), if any, is $6,000,000.
(4)	No separate registration fee is payable pursuant to Rule 457(g) under the Securities Act.