Published on May 14, 2008
Exhibit
32.1
CERTIFICATIONS
OF THE CHIEF EXECUTIVE OFFICER
UNDER
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002
In
connection with the filing by Lixte Biotechnology Holdings, Inc. (the
“Registrant”) of its Quarterly Report on Form 10-Q for the quarterly period
ended March 31, 2008 (the “Quarterly Report”) with the Securities and Exchange
Commission, I, John S. Kovach, certify, pursuant to 18 U.S.C. Section 1350,
as
adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002,
that:
(1)
The
Quarterly Report fully complies with the requirements of Section 13(a) or 15(d)
of the Securities Exchange Act of 1934; and
(2)
The
information contained in the Quarterly Report fairly presents, in all material
respects, the financial condition and results of operations of the
Registrant.
A
signed
original of this written statement required by Section 906 has been provided
to
the Registrant and will be retained by the Registrant and furnished to the
Securities and Exchange Commission or its staff upon request.
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Date:
May 13, 2008
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By:
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/s/
JOHN S. KOVACH
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John
S. Kovach
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Chief
Executive Officer and Chief Financial Officer
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(Principal
Executive Officer and Principal Financial
Officer)
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