Form: 10QSB

Optional form for quarterly and transition reports of small business issuers

May 21, 2007


Exhibit 32

Certification Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

In connection with the filing of the Quarterly Report on Form 10-QSB for the Quarterly Period Ended March 31, 2007 (the “Report”) by Lixte Biotechnology Holdings, Inc., the undersigned hereby certifies that:

1.
The Report complies in all material respects with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended, and
 
2.
The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of Registrant.
 
     
Date: May 18, 2007
   /s/ John S. Kovach 
 
John S. Kovach
 
Chief Executive Officer and Chief Financial Officer
(Principal financial and accounting officer)