Published on April 19, 2007
Exhibit
        2.4
    WestPark
      Capital, Inc. Letterhead
    April
      17,
      2007
    Dr. John
      Kovach
    Lixte
      Biotechnology Holdings, Inc.
    248
      Route
      25A, No.2
    East
      Setauket, New York 11733
    Dear
      Dr.
      Kovach:
    Reference
      is made to Paragraph 4.11 of the Private Placement Engagement Agreement dated
      March 23, 2006 between WestPark Capital, Inc. (“WestPark”) and Lixte, Inc.
      (the “Company”). Pursuant to that Section, the Company agreed to issue to
      WestPark certain warrants (the “Warrants”) and grant to WestPark standard demand
      and piggyback registration rights with respect to the shares underlying the
      Warrants. This will confirm our understanding that neither the Company nor
      any
      affiliate of the Company will be liable to WestPark for monetary damages arising
      from the failure of the Company to have complied with the foregoing registration
      provision, and WestPark hereby waives any right to make any claim for monetary
      damages as a result of any such failure to have complied, it being understood
      that the sole remedy of WestPark shall be to seek equitable relief.
    Sincerely,
    | WestPark
                Capital, Inc. | |
| 
by /s/
                R.
                Rappaport                                       
                
 Richard
                Rappaport,  Chief
                Executive Officer |