NT 10-Q: Notice under Rule 12b25 of inability to timely file all or part of a form 10-Q or 10-QSB

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 12b-25

COMMISSION FILE NUMBER: 20-2903526

NOTIFICATION OF LATE FILING

(Check One) |_| FORM 10-K |_| Form 20-F |_| Form 11-K |X| Form 10-Q
|_| Form N-SAR

For Period Ended March 31, 2007

|_| Transition Report on Form 10-K
|_| Transition Report on Form 20-F
|_| Transition Report on Form 11-K
|_| Transition Report on Form 10-Q
|_| Transition Report on Form N-SAR
For the Transition Period Ended: _________________________________

READ ATTACHED INSTRUCTIONS BEFORE PREPARING FORM. PLEASE PRINT OR TYPE

Nothing in the form shall be construed to imply that the Commission
has verified any information contained herein.

If the notification relates to a portion of the filing checked above,
identify the Item(s) to which the notification relates:

PART I - REGISTRANT INFORMATION:

LIXTE BIOTECHNOLOGY HOLDINGS, INC. (formerly SRKP 7, Inc.)
Full Name of Registrant

248 Route 25A, No. 2
Address of principal executive offices:

East Setauket, New York 11733
City, State and Zip Code

PART II - RULES 12b-25(b) and (c)

If the subject report could not be filed without unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b), the following should
be completed. (Check appropriate box).

(a) The reasons described in reasonable detail in Part III of this form
could not be eliminated without unreasonable effort or expense;

|X| (b) The subject annual report, semi-annual report, transition report on
Form 10-K, Form 20-F, 11-K, Form N-SAR, or portion thereof, will be
filed on or before the fifteenth calendar day following the
prescribed due date; or the subject quarterly report or transition
report on Form 10-Q, or portion thereof will be filed on or before
the fifth calendar day following the prescribed due date; and

(c) The accountant's statement or other exhibit required by Rule
12b-25(b) has been attached if applicable.


PART III - NARRATIVE

State below in reasonable detail the reasons why the Form 10-K, 11-K, 10-Q,
N-SAR, or the transition report or portion thereof, could not be filed within
the prescribed time period. (Attach extra sheets if needed).

The Company has incurred a delay in assembling the information required to be
included in its March 31, 2007 Form 10-QSB Quarterly Report. The Company expects
to file its March 31, 2007 Form 10-QSB Quarterly Report within the allotted
extension period.

PART IV - OTHER INFORMATION

(1) Name and telephone number of person to contact in regard to this
notification

John Kovach (631) 942 7959
(Name) (Area Code) (Telephone Number)

(2) Have all other periodic reports required under Section 13 or 15(d) of the
Securities Exchange Act of 1934 or Section 30 of the Investment Company
Act of 1940 during the preceding 12 months or for such shorter period that
the registrant was required to file such reports been filed?

|X| Yes |_| No

(3) Is it anticipated that any significant change in results of operations
from the corresponding period for the last fiscal year will be reflected
by the earnings statements to be included in the subject report or portion
thereof?

|X| Yes |_| No

On June 30, 2006, the Registrant acquired all of the capital stock of Lixte
Biotechnology, Inc. ("Lixte") in a transaction accounted for as a reverse
merger. Lixte had limited operations through June 30, 2006.

If so, attach an explanation of the anticipated change, both narratively
and quantitatively, and, if appropriate, state the reasons why a
reasonable estimate of the results cannot be made:

LIXTE BIOTECHNOLOGY HOLDINGS, INC.
---------------------------------------------------------------------
Name of Registrant as Specified in Charter

Has caused this notification to be signed on its behalf by the undersigned
hereunto duly authorized.


Date: May 15, 2007 By /s/ John Kovach
------------------------------------
John Kovach, Chief Executive Officer